NGM Bio Announces Results From Phase 2 Study Of NGM282 In NASH Patients Demonstrating Clinically Significant Improvements In Liver Histology After 12 Weeks

SOUTH SAN FRANCISCO, Calif., April 14, 2018 /PRNewswire/ -- NGM Bio, a leading biotech company developing a portfolio of clinical-stage product candidates that modulate novel or previously intractable targets implicated in metabolic and other serious diseases, today announced data from a Phase 2 study of its lead product candidate, NGM282, demonstrating clinically meaningful improvements in histological measures of disease in nonalcoholic steatohepatitis (NASH) patients at twelve weeks.

NGM282, an analogue of the human hormone FGF19, showed a rapid and robust impact on both fibrosis stage and disease activity as measured by non-alcoholic fatty liver disease (NAFLD) activity score (NAS) in this open-label study of NGM282. Comprehensive data from this Phase 2 study will be presented in a plenary session at The International Liver Congress 2018 in Paris at 10:15 AM CEST today.